What Is Estramustine 140mg
Estramustine 140mg is a complex of 17-beta-estradiol and nornitrogen mustard linked by a carbamate ester bridge therefore, it has both cytotoxic and antigonadotropic effects.
Estramustine sodium phosphate is a pro-drug. After verbal administration, it is rapidly converted to estramustine, most of which is oxidized to another cytotoxic metabolite, estromustine. Estramustine and estromustine exert their cytotoxic effect by binding to tubulin and/or microtubuleassociated proteins, inducing depolymerization and cellular metaphase arrest.
estramustine tablets is a compound of oestradiol and normustine which readily dephosphorylates during absorption to give estramustine, oestrone analog, oestradiol and oestrone. The oestrodiols released facilitate the understanding of the alkylating agent Into the prostate cancer cells which Inhibits microtubule assembly. Its effects are weaker than most alkylating agents and oestradiols.
estramustine dose medication is used to treat some types of prostate cancer. In the body, estramustine breaks down into estrogens (estrone, estradiol) and a type of cancer pill (estromustine). This medication is thought to work by increasing estrogens, which interfere with prostate cancer, and by slowing/stopping the promotion of cancer cells.
Major & minor for estramustine side effects
- breast tenderness
- decreased interest in sex
- decreased sexual ability
- muscle weakness
- stomach upset
Do not smoke cigarettes or use tobacco. estramustine cost combined with smoking further increase your risk for stroke, blood clots, high blood pressure, and heart attacks.If you will be having surgery or will be confined to a chair or bed for a long time (e.g., a long plane flight), notify your doctor beforehand. Special precautions may requirement to be taken in these circumstances while you are taking this pill because of the increased risk for blood clots.
If you have diabetes, estramustine may affect your blood sugar. cheque your blood sugar regularly as directed and share the results with your doctor.If you are nearsighted or wear contact lenses, you may develop vision problems or trouble wearing your contact lenses. Contact your eye doctor if these problems occur.This medication may cause blotchy, gloomy areas on your face and skin (melasma).
Store the product in the refrigerator between 36-46 degrees F (2-8 degrees C) away from light and humidity. Do not store in the bathroom.Store the Canadian product between 36-77 degrees F (2-25 degrees C) away from light and humidity.
Do not store in the bathroom.Keep all pills away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so.
Properly discard this manufacture when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for additional details about how to safely discard your product.